Ibuprofen against altitude sickness

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Society & You - Health
Saturday, 17 March 2012 08:18

Ibuprofen against altitude sickness, a team from Stanford Hospital & Clinics has researched the positive effects of ibuprofen against altitude sickness. In Demedicina.com tell you more about ibuprofen and altitude sickness.  Ibuprofeno contra el  mal de altura

As we climb a mountain, the atmospheric pressure decreases and pressure of the oxygen we breathe. If oxygen decreases caused changes in health.

If these conditions are maintained for some time can become fatal. Mountaineers usually during their promotions are often subjected to periods of acclimatization to help their bodies adapt to low oxygen pressures.

What is altitude sickness?

Refers to reactions experienced by the body when exposed to altitude where there are low oxygen pressure. The evil of height generally occurs above 2,400 meters. Most people can climb to 2,400 meters, although some people may experience symptoms at lower altitudes.

Among the effects of altitude sickness if not treated early are pulmonary edema (EPA) or cerebral edema (HACE), which are potentially fatal.

ibuproeno  contra el mal de altura


- As you go higher the air density decreases. So close to 3,000 meters down the amount of oxygen. The aircraft despite its security measures typically fly at an altitude of 2,400 meters to avoid problems for passengers on long flights.

- Dehydration. As altitude increases the lungs lose a higher rate of water, which may contribute to symptoms of altitude sickness

- Physical strength, speed of ascent and individual susceptibility of the factors that influence or predispose some people more than others to suffer altitude sickness. If you ascend too quickly you have more options of getting altitude sickness.

- Although in many cases the symptoms are temporary and disappear when the person becomes acclimated to the altitude, in other cases the problem is compounded.


Ibuprofen against altitude sickness

Symptoms of altitude sickness are headaches, fatigue, vomiting, high of appetite, dizziness. The researcher Grant Lipman in his study to improve these symptoms found that ibuprofen a drug best known for its analgesic and inflammatory was beneficial against altitude sickness.

Lipman studied 86 men and women in a double blind study the effects of ibuprofen on altitude sickness. The experiment was conducted with a group taking a placebo and the other ibuprofen .

The experiment group traveled to the White Mountains near Bishop in California. They stayed overnight at about 4,100 meters high and took 400 mg of ibuprofen (and the other group a placebo)

The next morning they went to a ture of 3,566 meters and took a second dose at two in the afternoon. He later rose to 3,831 meters and took the third dose at 8 pm, spent the night on the mountain.


About 43% of people who took the drug had symptoms of altitude sickness, compared with 69% of those taking placebo. Ibuprofen reduced the symptoms of altitude sickness. Although the reduction was not considered statistically significant, those who took placebo appeared to show worse symptoms.

There are medications to treat symptoms such as acetazolamide but has side effects like fatigue or dizziness and dexamethasone is associated with hypoglycemia, insomnia, depression and delirium. Ibuprofen as Lipman is beneficial to combat altitude sickness.

We suggest that the availability of ibuprofen by itself is an attractive drug for people traveling to high altitudes. Besides ibuprofen is active when taken six hours before the rise compared to other drugs such as acetazolamide you have to take a day before starting the ascent.

The authors think that if they did experiments with 600 mg of ibuprofen could be more robust data, but against these benefits should be weighed against the possible increase in gastrointestinal and kidney problems in people who are dehydrated.

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